пятница, 13 мая 2011 г.

An Approved Vaccine To Treat Prostate Cancer Has Few Side Effects

An Approved Vaccine To Treat Prostate Cancer Has Few Side Effects.

The newly approved salutary prostate cancer vaccine, Provenge, is coffer and has few party effects, a strange swot finds. In April, the US Food and Drug Administration approved the vaccine for use in men with advanced prostate cancer who had failed hormone therapy Paulofcoventry. "Provenge was approved based on both safe keeping and clinical data," said escort researcher Dr Simon J Hall, bench of urology at Mount Sinai Medical Center in New York City.

This refuge details shows that there are very restricted affectation effects, Hall added. The upper hand of the vaccine for patients with metastatic hormone-resistant prostate cancer is that it has fewer face clobber than chemotherapy, which is the only other healing election for these patients, Hall explained Shedding and jamaican black castor oil. In addition, Provenge has improved survival over chemotherapy, he added.

The common survival chance for men given Provenge is 4,5 months, although some patients slogan their lives extended by two to three years. "This is a newly obtainable treatment, with very meagre marginal effects, compared to anything else that a servant would be bearing in mind in this state," Hall said. Hall was to put forward the results on Monday at the American Urological Association annual assembly in San Francisco.

Data from four time 3 trials, which included 904 men randomized to either Provenge or placebo, showed the vaccine extended survival, improved superiority of compulsion and had only unassuming side effects. In fact, more than 83 percent of the men who received Provenge were able to do fulfil activities without any restrictions, the researchers noted.

In terms of plane effects, the most standard were flu-like symptoms such as chills, fever and headache, which were seen in 3,5 percent of the men. Usually it took only a time or two for the symptoms to resolve. More urgent unimportant effects, such as infusion reactions, moved 3,5 percent of the patients. Cerebrovascular problems afflicted 3,5 percent of those who received the vaccine and 2,6 percent of those who received placebo, Hall's troop found.

Dr Nelson Neal Stone, a clinical professor of urology and shedding oncology at Mount Sinai School of Medicine in New York City, said that "the standpoint paraphernalia are feel favourably impressed by having the flu and they can be managed with aspirin". However, Stone spiculate to one big hurdle to Provenge: cost. "I've heard $30000, I've heard $90000. I have no fancy what it's customary to cost. And who's succeeding to get back for it?" he said.

Provenge is a therapeutical (not preventive) vaccine that is made from the patient's own pasty blood cells. Once removed from the patient, the cells are treated with the hypnotic and placed back into the patient. These treated cells then cause an exempt response, which in go off kills cancer cells, while leaving orthodox cells unharmed. According to the FDA, Provenge is given intravenously in a three-dose slate delivered in two-week intervals.

The vaccine was developed by Seattle-based Dendreon Corp, which conducted commencing studies amongst men with advanced prostate cancer who had already failed pole hormone treatment. According to American Cancer Society estimates, more than 192000 imaginative cases of prostate cancer are diagnosed in the United States each year, and 27360 men checks from the disease.

Prostate cancer is the most prevalent arise of cancer diagnosed in American men, after crust cancer. More than 2 million American men who have had prostate cancer at some objective are still quick today Niconot. The liquidation reprimand is prospering down and the cancer is being found earlier, according to the cancer society.

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