Use Of Medicines For Epilepsy During Pregnancy Can Cause A Risk To The Child

Use Of Medicines For Epilepsy During Pregnancy Can Cause A Risk To The Child.


Pregnant women with epilepsy who are attractive carbamazepine (Tegretol) to mechanism seizures may be at a measure increased gamble of having an infant with spina bifida, a budding sanctum finds. Spina bifida is a train in which the bones of the spinal column do not close but the spinal rope remains in place, usually with flay covering the defect advair diskus drug. Most children will miss lifelong treatment for problems arising from spoil to the spinal cord and spinal nerves.



And "For women with epilepsy, confiscation control during pregnancy is very important," said clue researcher Lolkje de Jong-van den Berg, from the splitting of drugstore at the University of Groningen in the Netherlands. "Our investigate can help in decisions regarding whether carbamazepine should be the analgesic of choice in pregnancy" fat tumblr. However, the best opportunity regarding treatment can be chosen only on an individual foundation by the woman and her neurologist before pregnancy, weighing the benefits of epilepsy mastery against the risk of birth defects, de Jong-van den Berg said.



The communication is published in the Dec 3, 2010 online printing of the BMJ. For the study, de Jong-van den Berg's side reviewed existing investigating to conclude the peril of birth defects among women winsome Tegretol. The researchers found that infants of women compelling Tegretol were 2,6 times more tenable to have spina bifida, compared with women not captivating any anti-epileptic medication.



However, the risk associated with Tegretol was less than with another anti-epileptic drug- valproic acid (Depakene). In fact, Tegretol was less dicey than valproic acid when it came to other parentage defects such as hypospadias, where a boy's urinary beginning develops in the indecorous her of the penis or in the scrotum. "Carbamazepine is specifically tied up to an increased risk of spina bifida," de Jong-van den Berg said. "But you have to tower in feeling that the absolute risk is small".